OpenAI has introduced Prism, a free, web-based workspace for scientific writing and collaboration that integrates GPT-5.2 into the drafting process and is available to anyone with a ChatGPT personal account.
Prism is built as a cloud, LaTeX-native environment where the model works inside the project rather than in a separate chat window.
OpenAI says Prism can draft and revise text using the full document as context, handle equations and references, search and incorporate related literature and convert whiteboard equations or diagrams into LaTeX.
A workflow play, not autonomous science
OpenAI claims that Prism is an answer to “fragmented” research work that forces scientists to jump between editors, compilers, PDFs, reference managers and chat tools.
The tool was developed following OpenAI’s acquisition of Crixet, a cloud-based LaTeX platform. By evolving Crixet’s infrastructure into Prism, OpenAI integrated AI model assistance directly into the existing typesetting workflow, allowing researchers to remain in their native format.
That’s similar to how AI coding tools took off: strong models built directly into developers’ workflows. OpenAI’s Kevin Weil wrote “2026 will be for AI and science what 2025 was for AI and software engineering.”
If we look at data, OpenAI claims that ChatGPT sees almost 8.4 million messages on advanced topics in the sciences and mathematics from roughly 1.3 million weekly users.
Competitor landscape
Other frontier AI vendors are also pushing “AI-in-the-workflow,” but through different surfaces. Google positions NotebookLM as a research notebook that works from a user’s selected sources.
Microsoft is embedding Copilot directly into Office apps like Word and Excel. Anthropic’s Claude Projects organizes work into shared, persistent project contexts. Perplexity’s Create files and apps focuses on generating finished artifacts like reports from guided research.
What enterprise R&D teams should watch
For corporate research groups, OpenAI is emphasizing context persistence, saying the model can reason with the full structure of a paper, including equations, citations, figures and surrounding text.
OpenAI says Prism will be available “soon” to ChatGPT Business, Enterprise and Education customers, but the launch post does not spell out enterprise-grade controls such as audit logging, retention settings or admin policy enforcement.
CFO Sarah Friar wrote that as AI moves into science and drug discovery, new economic models like licensing and “outcome-based pricing” will emerge to “share in the value created.
In a Dec. 2025 arXiv paper on learning-curve monotonicity, the authors wrote that results were derived by “variants of GPT-5.2 Pro,” with humans prompting, verifying and transcribing proofs, an example OpenAI separately highlighted as a template for supervised collaboration.